Synthesis, Identification and biological study of Some mixed ligand complexes of tridentate heterocyclic azo ligands

Abstract

     azo imidazole ligand has been prepared by diazolation of  2-amino benzoic acid and coupling the diazonium salt that formed with 4,5diphenyl imidazole as coupling base, the complexes of  Ni(II), Cu(II), Zn(II), Hg(II) synthesized by mixing a calculated amount of these ion salt solutions with a mixture of azo imidazole ligand that prepared and azo pyridyl dye (PAN) solution with molar ratio (1: 1: 1).  Several spectral techniques used to characterization these compounds include: FT-IR , UV-VIS the magnetic susceptibility ,C.H.N analysis ,atomic absorption and molar conductivity, The results confirmed both ligands behave as tridentale ligands type (N,N,O) and all complexes of mixed tridentate azo ligands that prepared have octahedral geometry. The antimicrobial activity of the ligands and their mixed ligand complexes was studied against five types of pathogemic bacteria (Enterococcus fecalius , Staphylococcus haemolyticus , Staphylococcus warneri, Escherichia coli, Klebsilla Pneumonia). Furthermore , the antifungal activity against two fungi (Aspergillus flavus and Aspergillus terreus) was studied .