A comparative study between propofol vs. thiopentone plus Lidocaine effects on hemodynamic changes during laryngeal mask airway (LMA) insertion in urological surgery in Baghdad hospital.

Zina Tariq Ali


         During the induction of general anesthesia, the stability of hemodynamic parameters is very important. In an idealy, all patients would be care by their anesthetists adequately to reduce all risks without interfering with the soft running of the operating list. The hemodynamic instability throughout anesthesia can be decrease by using numerous pharmacological agents and combinations have been prepared for that. Thiopentone and Propofol are intravenous anesthetics having comparatively diverse hemodynamic influences and adverse effects. Appropriate maintenance of airways securing during surgical operations is considered as the basic fundamental responsibility of an anesthesiologist. By using the modern laryngeal mask airway (LMA) with sufficient muscle relaxation, appropriate anesthetic depth and airways reflexes depression, the common problems of airway management as well as the complications after LMA insertion procedure are preventing. Our study aimed to assess the comparison effects of two anesthetic induction agents (propofol vs. thiopental- lidocaine admixture on the hemodynamic changes (heart rate (H.R), respiratory rate (R.R), oxygen saturation (SpO2), Blood pressure systolic (S.B.P) and diastolic (D.B.P) during LMA insertion for four (4) different time intervals (pre induction, at induction, at LMA insertion as well as after 5 min after LMA insertion). The current study was enrolled in Baghdad educational  hospital includes one hundred fifty (150) patients who were divided into equally groups, (115 male and35 female)75 for each group, aged (20-60) years, all patients were submit to ASA (I, II), physical grade planned for elective surgical operations under general anesthesia(G.A). All the patients were evaluated clinically, assessed and investigated prior to surgery. The allergic history or adverse reactions of barbiturate or propofol were excluded. Patients were divided into: Group (A) is receiving 2.5mg/kg (I .V) of propofol as an induction agent (n=75), and Group (B) is receiving 5mg/kg (I.V) thiopentone plus lidocaine2mg as an induction agent also (n=75). The induction induces by either propofol or thiopentone as induction agent.

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